Towards Selective Immunomodulation of Microglia: Are Fc Receptors (FcRs) for Immunoglobulins Attractive Candidate Targets

Time: 1:30 pm
day: Day Two


  • Effectively and selectively blocking microglia pathogenic contributions in disease state is a very attractive therapeutic opportunity for neurodegenerative and neuroinflammatory diseases
  • Outlining the role of Fc-receptors (FcRs) in the CNS and microglia in developing neurological disease pathology
  • Utilizing a novel preclinical model, to support the first evidence for FcR-dependent functions in microglia and how autoantibodies and FcR-signaling modulate microglia physiology in the CNS